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Biomarker Testing

Biomarkers are an integral part of the clinical management of a cancer patient’s treatment journey. Learn more about how biomarker testing can detect tumor mutations and inform care management.

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The Role of Biomarkers in Cancer Care
PIK3CA and Testing

The Role of Biomarkers in Cancer Care

Biomarkers consist of 2 separate groups1

A biomarker – an objectively measured characteristic evaluated as an indicator of normal biological processes, or pharmacologic responses to a specific therapeutic intervention – can provide information that is1:

  • Prognostic: informs the patient’s overall cancer outcome, regardless of therapy1
  • Predictive: informs the effect of a therapeutic intervention in a patient1

Clinically relevant biomarkers have been identified in numerous malignancies2

  1. Oldenhuis CN, et al. Prognostic versus predictive value of biomarkers in oncology. Eur J Cancer. 2008; 44(7):946-953.
  2. US Food and Drug Administration. Table of Pharmacogenomic Biomarkers in Drug Labeling. Accessed April 5, 2024. https://www.fda.gov/drugs/​science-and-research-drugs/​table-pharmacogenomic-biomarkers-drug-labeling.

PIK3CA and Testing

Learn more about the PI3Kinase pathway and PIK3CA mutation testing in breast cancer:

To view a PDF of the above document, please click here.

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